It is true that insanity may originate in the mind, as well as in the body, but diseased action must take place in the brain, otherwise we have not, as has been well observed, “a true psychopathy.”
1861, Alex John Sutherland, “Croonian Lectures. On the Pathology, Morbid Anatomy, and Treatment of Insanity”, in The Journal of Mental Science, volume 7, number 36, Association of Medical Officers of Asylums and Hospitals for the Insane, retrieved 2021-03-01, page 162